Plaster containing felbinac

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

Reexamination Certificate

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Details

C424S443000, C424S448000

Reexamination Certificate

active

06844007

ABSTRACT:
A plaster comprising a styrene-isoprene-styrene block copolymer 10-40 wt %, a rosin-based resin 5-30 wt %, a plasticizer 20-70 wt %, polyisobutylene 6-40 wt %, an antioxidant 0.1-5 wt %, and felbinac as a medicinally effective component 1.1-10 wt %, wherein the plaster does not contain crotamiton which is a solubilizer for the felbinac, the felbinac is uniformly dispersed in a semi-solubilized state in the plaster, wherein solubilized felbinac and microcrystalline felbinac coexist in the plaster, and a thickness of the plaster is 50-300 μm.

REFERENCES:
patent: 4455146 (1984-06-01), Noda et al.
patent: 4478567 (1984-10-01), Nakagawa et al.
patent: 5519046 (1996-05-01), Noda et al.
patent: 5725874 (1998-03-01), Oda et al.
patent: 5869087 (1999-02-01), Hirano et al.
patent: 0 781 553 (1997-07-01), None
patent: 4-321624 (1992-11-01), None
patent: 5-139962 (1993-06-01), None
patent: 8-295624 (1996-11-01), None
patent: WO 9608245 (1996-03-01), None
International Search Report—PCT/JP97/04439.

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