Plasminogen activator

Details Plasminogen activator Plasminogen activator

1990-06-14

1992-11-03

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

435215, A61K 3754, C12N 972

Patent

active

051607352

ABSTRACT:
A novel plasminogen activator which is identical in peptide sequence to naturally occurring human prourokinase except that the 155th amino acid counting from the N-terminal amino acid (serine) is other than the 155th amino acid (proline) of naturally occurring human prourokinase, optionally with the addition of methionine at the N terminus.

REFERENCES:
Schechter et al., Biochem. & Biophys. Res. Comm., vol. 27 No. 2 pp. 157-162 (1967).
Poszgay et al., Eur. J. Biochem., vol. 115, pp. 491-495 (1981).
Chang, Eur. J. Biochem., vol. 151, pp. 217-224 (1985).

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