Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Patent
1994-05-12
1996-08-13
Nucker, Christine M.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
4242771, 435 6, C07K 1400, C12Q 168
Patent
active
055457177
ABSTRACT:
Disclosed are substantially pure plasmilar polypeptide and antibodies which bind plasmilar.
REFERENCES:
Ichinose, Biochemistry 31, 3113 (1992)., "Multiple Members of the Plasminogen-Apolipoprotein(a) Gene Family Associated with Thrombosis,".
Forsgren et al. FEBS Lett. 213:254-260 (1987)., "Molecular cloning and characterization of a full-length cDNA clone for human plasminogen".
Horlow et al. "Antibodies: A laboratory manuel, Cold Spring Harbor Laboratories", (1988).
Robbins et al., "NH.sub.2 -Terminal Sequences of Mammalian Plasminogens and Plasmin S-Carboxymethyl Heavy (A) and Light (B) Chain Derivatives," J. Biol. Chem.; 248:7242-7246 (1973).
Hoylaerts et al., "Kinetics of the Activation of Plasminogen by Human Tissue Plasminogen Activator," J. Biol. Chem.; 257:2912-2919 (1982).
Saksela, "Plasminogen activation and regulation of pericellular proteolysis," Biochem. Biophys. Acta., 823: 35-65 (1985).
Holvoet et al., "A Monoclonal Antibody Specific for Lys-plasminogen," J. Biol. Chem.; 260:12106-12111 (1985).
McLean et al., "cDNA sequence of human apolipoprotein(a) is homologous to plasminogen," Nature; 330:132-137 (1987).
Treadwell et al., "Cartilage Synthesizes the Serine Protease Inhibitor PAI-1: Support for the Involvement of Serine Proteases in Cartilage Remodeling," J. Ortho. Research; 9:309-316 (1991).
Petersen et al., "Characterization of the Gene for Human Plasminogen, a Key Proenzyme in the Fibrinolytic System," J. of Biological Chemistry 265:6104-6111, (1990).
Patthy et al., "Kringles:modules specialized for protein binding," FEBS Letters; 171:131-136 (1984).
Nakamura et al., "Molecular cloning and expression of human hepatocyte growth factor," Nature; 342:440-443 (1989).
Moscatelli et al., "Membrane and matrix localization of proteinases: a common theme in tumor cell invasion and angiogenesis," Biochimica et Biophysica Acta.; 948:67-85 (1988).
Collen et al., "Basic and Clinical Aspects of Fibrinolysis and Thrombolysis," Blood; 78:3114-3124 (1991).
Eeckhout et al., "Further Studies on the Activation of Procollagenase, the Latent Precursor of Bone Collagenase," J. Biochem; 166:21-31 (1977).
Liotta et al., "Cancer Metastasis and Angiogenesis: An Imbalance of Positive and Negative Regulation," Cell; 64:327-336 (1991).
Werb et al., "Endogenous Activation of Latent Collagenase by Rheumatiod Syynovial Cells," New England Journ. of Medicine; 296:1017-1023 (1977).
Miyazawa et al., "Molecular Cloning and Sequence Analysis of cDNA for Human Hepatocyte Growth Factor," Biochem. and Biophys. Research Comm.; 163:967-973 (1989).
Matrisian, "Metalloproteinases and their inhibitors in matrix remodeling," Reviews; 6:121-125 (1990).
Cruwys et al., "Cooperation between interleukin-1 and the fibrinolytic system in the degradation of collagen by articular chondrocytes," J. Pharmacol; 100:631-635 (1990).
Wiman et al., "Amino-Acid Sequence of the Cyanogen-Bromide Fragment from Human Plasminogen that Forms the Linkage between the Plasmin Chains," J. Biochem.; 58:539-547 (1975).
Wiman, "Primary Structure of the B-Chain of Human Plasmin," Eur. J. Biochem.; 76:129-137 (1977).
Wiman et al., "Structural Relationship between `Glutamic Acid` and `Lysine` Forms of Human Plasminogen and Their Interaction With the NH.sub.2 -Terminal Activation Peptide . . . ," Eur. J. Biochem.; 50:489-494 (1975).
Tryggvason et al., "Proteolytic degradation of extracellular matrix in tumor invasion," Biochem. Biophys. Acta. 907:191-217 (1987).
Carroll, II Lawrence J.
Nucker Christine M.
The General Hospital Corporation
LandOfFree
Plasmilar and plasmilar antibody compositions as malignant cell does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Plasmilar and plasmilar antibody compositions as malignant cell , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Plasmilar and plasmilar antibody compositions as malignant cell will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1048627