Plasmid vectors encoding a protein of a picornavirus

Details Plasmid vectors encoding a protein of a picornavirus Plasmid vectors encoding a protein of a picornavirus

1991-09-20

1993-01-26

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Vector, per se

C12N 1585

Patent

active

051822113

ABSTRACT:
The invention relates to an active principle of a vaccine, in which the characteristic epitope is incorporated in the capsid of a picornavirus, in particular of poliovirus, used as a vector. This active principle consists of a viable hybrid picornavirus containing an epitope characteristic of a vaccinating protein, and heterologous with respect to the proteins of this picornavirus, in place of one of its own immunogenic epitopes.

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