Plasmid encoding the Pseudomonas mendocina toluene monooxygenase

Details Plasmid encoding the Pseudomonas mendocina toluene monooxygenase Plasmid encoding the Pseudomonas mendocina toluene monooxygenase

1988-04-05

1991-05-21

Teskin, Robin L.

Chemistry: molecular biology and microbiology

Vector, per se

435 691, 435 112, 435189, 43525234, 435874, 935 16, 935 29, 935 39, 935 56, 935 61, 935 72, 935 82, C12N 100, C12N 902, C12N 122, C12P 2106, C12P 2104, C12R 138

Patent

active

050174959

ABSTRACT:
Disclosed and claimed are DNA gene segments, biologically functional plasmids and recombinant plasmids, and microorganism host cells containing such plasmids, all of which contain toluene monooxygenase genes from Pseudomonas mendocina KR-1 and which are useful in a method for the microbial bioconversion of selected phenyl compounds to selected phenolic compounds. In particular, the method is useful for making p-hydroxyphenylacetic acid which is a valuable chemical intermediate in the preparation of certain antibiotics and certain .beta.-adrenergic blocking agents.

REFERENCES:
Whited, G. M., Ph.D. Thesis, Univ. of Texas at Austin, Dissertation Abstracts International, p. 1861, vol. 47/05-B, (1986).

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