Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Patent
1980-05-07
1984-02-07
Naff, David M.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
435 68, 435172, 435317, C12N 120, C12N 1500, C12N 100, C12P 2100
Patent
active
044304340
ABSTRACT:
Plasmid conferring resistance to streptomycin (Sm.sup.R) and neomycin (Neo.sup.R) upon its host (e.g. a Bacillus, Staphylococcus or Escherichia coli) and which after having taken up a foreign DNA fragment at one of its restriction sites with loss of its Sm.sup.R or Neo.sup.R phenotype, is still capable of replicating and expressing genetic information in its host.
REFERENCES:
patent: 4237224 (1980-12-01), Cohen et al.
Barth; in Plasmids of Medical, Environmental, and Commercial Importance, Timmis et al., (ed.), Elsevier/North-Holland, Amsterdam, 1979, pp. 399-410.
Gryczan et al., J. Bact. 134, 318 (1978).
Keggins et al., Proc. Natl. Acad. Sci. U.S.A. 75, 1423 (1978).
Suttcliffe et al., in Genetic Engineering, Chakrabarty (ed.), CRC Press, 1979, pp. 83-101.
Docherty Andrew J. P.
Sanders Johan P. M.
Adams Bruce L.
Burns Robert E.
Gist Brocades NV
Lobato Emmanuel J.
Martinell James
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