Plasmapheresis system and method

Liquid purification or separation – Casing divided by membrane into sections having inlet – Energy recovery from treated liquid

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

2104161, 2103601, 21032175, B01D 1300

Patent

active

048062472

ABSTRACT:
A reliable flow rate plasmapheresis system includes a rotating enhanced vortex type of membrane filter coupled to receive a flow of anticoagulated whole blood and separate concentrate and filtrate in responses thereto. An anticoagulant pump is coupled to mix controlled amounts of anticoagulant with the input blood flow. Degradation of plasma flow rate during multiple extraction-reinfusion cycles is inhibited by selecting the starging anticoagulant pH value and controlling the anticoagulant flow rate relative to the whole blood to establish a final whole blood/plasma pH value in the range of 6.8 to 7.2, with an anticoagulant to blood ratio in the range of 1:6 to 1:25.

REFERENCES:
patent: 3634228 (1972-01-01), Latham, Jr.
Murphy, S. et al., "Storage of Platelets at 22.degree. C.", Blood, vol. 35, p. 549 (1970).
Murphy, S. and Gardner, F., "Platelet Storage at 22.degree. C.: Role of Gas Transport Across Plastic Containers in Maintenance of Viability", Blood, vol. 46, p. 209 (1975).
Schlicter, S., "Preservation of Platelet Viability and Function During Storage of Concentrates", The Blood Platelet in Transfusion Therapy, Alan R. Liss, Inc., NY pp. 83-100 (1978).
Rock, G. and Figuerdo, A., "Metabolic Changes During Platelet Sotrage", Transufsion, vol. 16, p. 571 (1976).
Holme, S. et al., "Platelet Storage at 22.degree. C.", Blood, vol. 52, p. 425 (1978).
Koerner, K., "Platelet Function After Shipment of Room Temperature Platelet Concentrates", Vox Sang, vol. 44, p. 37 (1983).
Heal, J., et al., "Non Centrifugal Plasma Collection Using Cross Flow Membrane Plasmapheresis", Vox Sang, vol. 44, p. 156 (1983).
Witbank, T. et al., "Filtration Plasmapheresis In Vivo", Transfusion, vol. 21, p. 502 (1981).
Chimel, H., "The Effects of Pressure, Flow Consideration, and Surface Composition on the Filtration Properties of Plasma Filtration Modules", Plasma Therapy Trans. Tech., vol. 4, p. 381 (1983).
Forstrom, R. et al., "Formed Element Deposition onto Filtering Walls", Trans. Am. Soc. Artif. Int. Organs, vol. XXI, pp. 602-607 (1975).
Lopez-Leiva, "Ultrafiltration at Low Degrees of Concentration Polarization: Technical Possibilities", pp. 210-651 (Dec. 1980).
Dorson, Int. Appln. WO/82/03567 (Oct. 1982).
English Language Abstracts from Derwent World Patent Index, 1963-1980 (1 page).
Supplementary European Search, Report, European Patent Office, (5 pages).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Plasmapheresis system and method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Plasmapheresis system and method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Plasmapheresis system and method will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1520308

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.