Chemistry: molecular biology and microbiology – Differentiated tissue or organ other than blood – per se – or... – Including perfusion; composition therefor
Patent
1997-07-02
1999-08-31
Saucier, Sandra E.
Chemistry: molecular biology and microbiology
Differentiated tissue or organ other than blood, per se, or...
Including perfusion; composition therefor
604 4, 435 2, A01N 102, A61M 3700
Patent
active
059452722
ABSTRACT:
A blood substitute solution and methods for its use are provided. The subject solution contains: subphysiological amounts of potassium ion, 0-10 mM magnesium ion, 70-160 mM sodium ion, 0.5-4.0 mM calcium ion, and 80-170 mM chloride ion; one or more water soluble oncotic agents; an organic carboxylic acid or salt thereof; physiological amounts of a sugar; and a blood clotting factor. The subject solution is further characterized in that it does not include a conventional biological buffer. The subject solutions find use in a variety of different applications, e.g. as blood volume expanders, and the like.
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Segall Judith M.
Segall Paul E.
Sternberg Hal
Waitz Harold D.
BioTime, Incorporated
Field Bret
Saucier Sandra E.
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