Plasma-enhanced functionalization of carbon-containing...

Stock material or miscellaneous articles – Coated or structually defined flake – particle – cell – strand,... – Particulate matter

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S174000, C435S176000, C977S847000, C977S890000

Reexamination Certificate

active

10807914

ABSTRACT:
Methods for producing plasma-treated, functionalized carbon-containing surfaces are provided. The methods include the steps of subjecting a carbon-containing substrate to a plasma to create surface active sites on the surface of the substrate and reacting the surface active sites with stable spacer molecules in the absence of plasma. Biomolecules may be immobilized on the resulting functionalized surfaces. The methods may be used to treat a variety of carbon-containing substrates, including polymeric surfaces, diamond-like carbon films and carbon nanotubes and nanoparticles.

REFERENCES:
patent: 4568706 (1986-02-01), Noetzel et al.
patent: 4737544 (1988-04-01), McCain et al.
patent: 5071909 (1991-12-01), Pappin et al.
patent: 5079156 (1992-01-01), Mauz et al.
patent: 5080924 (1992-01-01), Kamel et al.
patent: 5132108 (1992-07-01), Narayanan et al.
patent: 5306768 (1994-04-01), Hsu et al.
patent: 5308641 (1994-05-01), Cahalan et al.
patent: 5316784 (1994-05-01), Maurer et al.
patent: 5336518 (1994-08-01), Narayanan et al.
patent: 5438077 (1995-08-01), Komiya et al.
patent: 5853744 (1998-12-01), Mooradian et al.
patent: 5880552 (1999-03-01), McGill et al.
patent: 5897955 (1999-04-01), Drumheller
patent: 6022902 (2000-02-01), Koontz
patent: 6133436 (2000-10-01), Koster et al.
patent: 6143354 (2000-11-01), Koulik et al.
patent: 6159531 (2000-12-01), Dang et al.
patent: 6306506 (2001-10-01), Timmons et al.
patent: 6332363 (2001-12-01), Molloy et al.
patent: 6402899 (2002-06-01), Denes et al.
patent: 6528020 (2003-03-01), Dai et al.
patent: 6528264 (2003-03-01), Pal et al.
patent: 6602692 (2003-08-01), Glusenkamp et al.
patent: 6630358 (2003-10-01), Wagner et al.
patent: 2003/0163198 (2003-08-01), Morra et al.
patent: 0874242 (1998-10-01), None
Rasmussen, et al., “Covalent Immobilization of DNA into Polystyrene Microwells: The Molecules are only Bound at the 5′ End,”Analytical Biochemistry, 198, pp. 138-142, 1991. Published by Academic Press, Inc. 21.
Timofeev, et al., “Regioselective Immobilization of Short Oligonucleotides to Acryl Copolymer Gels,”Nucleic Acids Research, 24, No. 16, pp. 3142-3148, 1996. Published by Oxford University Press.
Proudnikov, et al., “Chemical Methods of DNA and RNA Fluorescent Labeling,”Nucleic Acids Research, 24, No. 22, pp. 4535-4532, 1996, Published by Oxford University Press.
Parinov, et al., DNA Sequencing by Hybridization to Microchip Octa- and Decanucleotides Extended by Stacked Pentanucleotides,Nucleic Acids Research, 24, No. 15, pp. 2998-3004, 1996. Published by Oxford University Press.
Guschin, et al., Manual Manufacturing of Oligonucleotide, DNA and Protein Microchips,Analytical Biochemistry, 250, pp. 203-211, 1997. Published by Academic Press.
Fotin, et al., “Parallel Thermodynamic Analysis of Duplexes on Oligodeoxyribonucleotide Microchips,”Nucleic Acids Research, 26, No. 6, pp. 1515-1521, 1998. Published by Oxford University Press.
Proudnikov, et al., Immobilization of DNA in Polyacrylamide Gel for the Manufacture of DNA and DNA-Oligonucleotide Microchips,Analytical Biochemistry, 259, pp. 34-41, 1998. Published by Academic Press.
Wang, et al., “Polishable and Renewable DNA Hybridization Biosensors,”Anal Chem, 70, pp. 3699-3702, 1998. Published by the American Chemical Society.
Alvarez-Blanco, et al., “A Novel Plasma-enhanced Way for Surface-functionalization of Polymeric Substrates,”Polymer Bulletin, 47, pp. 329-336, 2001. Published by Sprinter-Verlag.
Ivanova, et al., Feasibility of Using Carboxylic-rich Polymeric Surfaces for the Covalent Binding of Oligonucleotides for microPCR Applications,Smart Mater. Struct., 11, pp. 783-791, 2002. Published by Institute of Physics Publishing.
Metzger, et al., Signal to Noise Comparison Accelr8 OptArray vs. The Leading Polymer and Silane Microarray Slide Chemistries,Technical Bulletin, No. TB0400, 2002.
Yang, et al., “DNA-modified Nanocrystalline Diamond Thin-films as Stable, Biologically Active Substrates,”Nature Materials, 1, No. 4, pp. 253-257, 2002. Published by Nature Publishing Group.
Liu, et al., “DNA Probe Attachment on Plastic Surfaces and Microfluidic Hybridization Array Channel Devices with Sample Oscillation,”Analytical Biochemistry317, pp. 76-84, 2003. Published by Academic Press.
http://www.surmoodics.com/pageDetail.aspx?pageId=10&menuID=10—“Biomolecule Immobilization”, website article printed on Feb. 19, 2004.
http://www.surmodics.com/pageDetail.aspx?pageId=7&menulID=7—“Photolink Manufacturing Process”, website article printed on Feb. 19, 2004.
http.//www/vwrcanlab.com- “A Specific Surface for a Specific Application.” Website.
Podyminogin, et al., “Attachment of Benzaldehyde-modified Oligodeoxynucleotide Probes to Semicarbazide-Coated Glass,”Nucleic Acids Research, vol. 29, No. 24, pp. 5090-5098, 2001. Published by Oxford University Press.
Cheung, et al., “5′-Thiolated Oligonucleotides on (3-Mercaptopropyl) trimethoxysilaten-Mica: Surface Topography and Coverage,” printed from Web, Jun. 5, 2003. Published by American Chemical Society.
“Motorola Goes for Organic Growth with Biochips,” http://www.groupweb.com/sci—tech/jun—30/motorola.html Website article printed on Jan. 2, 2000.
“Motorola's Biochip Center Aims for a Healthier World,” http://www.edtn.com/story/tech/OEG19990216S0030-R. Website article printed on Aug. 6, 2004.
“EasySpot Microarray Slide,” http://www.u-vision-biotech.com/english/product—service/easy—oligo. Website article printed on Feb. 19, 2004.
“Novel surface chemistry for DNA immobilization,” http://hamers.chem.wisc.edu/research/bioattachment/dna—on—silicon.htm. Website article printed on Mar. 2, 2003.
“Motorola and Packard to produce ‘biochips’” http://www4.nando.net
ewsroom
tn/health/062998/health7—12937—noframes.html. Website article printed on Jan. 2, 2000.
http://www.whatis.com/biochip.html. Website article printed on Jan. 2, 2000.
“New “Biochips” Aimed at Medicine, Agriculture,” http://www.pcworld.com/pcwtoday/article/0,1510,7313,00.html. Website article printed on Jan. 2, 2000.
http://arrayit.com/Products/Substrates/. Website article printed on Aug. 9, 2004.
http://arrayit.com/Products/Substrates/SME/sme.html. Website article printed on Aug. 6, 2004.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Plasma-enhanced functionalization of carbon-containing... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Plasma-enhanced functionalization of carbon-containing..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Plasma-enhanced functionalization of carbon-containing... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3850899

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.