Plasma-based platelet concentrate preparations with additive

Details Plasma-based platelet concentrate preparations with additive Plasma-based platelet concentrate preparations with additive

1994-06-16

1995-12-12

Knode, Marian C.

Chemistry: molecular biology and microbiology

Maintaining blood or sperm in a physiologically active state...

424532, A01N 102

Patent

active

054748917

ABSTRACT:
The present invention provides a composition and method for improving the storage of platelets and optimizing the viability of stored platelets. The present invention allows platelets to be stored in plasma for extended periods, without the addition of buffer, by adding storage extension additives, which include acetate, pyruvate, acetoacetate, .beta.-hydroxybutyrate, acetone, .alpha.-ketoglutarate, succinate, fumarate, malate, oxaloacetate, C.sub.3-8 fatty acid anions, triose phosphates and mixtures thereof, to a platelet concentrate.

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