Plaque inhibiting oligosaccharide

Details Plaque inhibiting oligosaccharide Plaque inhibiting oligosaccharide

1991-09-12

1993-03-02

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Dentifrices

536123, 424 48, 424 50, 514 54, A61K 3170, A61K 600

Patent

active

051907461

ABSTRACT:
A purified oligosaccharide consisting of a hexasaccharide with a native molecular weight of 959 which can be isolated from the cell walls of Streptococcus oralis. The oligosaccharide is able to significantly block the interaction between the human oral plaque bacteria Streptococcus oralis H1 and Capnocytophaga ochracea ATCC 33596. This purified oligosaccharide contains saccharide components found to inhibit many know interactions between plaque bacteria and may be effective in prevention, inhibition and reversal of dental plaque deposits. The oligosaccharide may be applied effectively when incorporated in toothpastes, mouth wash, etc.

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