Plant sterol acyltransferases

Details Plant sterol acyltransferases Plant sterol acyltransferases

2006-10-18

2009-10-13

Kallis, Russell (Department: 1638)

Multicellular living organisms and unmodified parts thereof and

Method of introducing a polynucleotide molecule into or...

The polynucleotide alters fat, fatty oil, ester-type wax, or...

C800S287000, C800S298000, C435S419000, C435S320100, C536S023100, C536S023200, C536S023600

Reexamination Certificate

active

07601890

ABSTRACT:
The present invention is directed to lecithin:cholesterol acyltransferase-like polypeptides (LCAT) and acyl CoA:cholesterol acyltransferases-like polypeptides (ACAT). The invention provides polynucleotides encoding such cholesterol:acyltransferases-like polypeptides, polypeptides encoded by such polynucleotides, and the use of such polynucleotides to alter sterol composition and oil production in plants and host cells. Also provided are oils produced by the plants and host cells containing the polynucleotides and food products, nutritional supplements, and pharmaceutical composition containing plants or oils of the present invention. The polynucleotides of the present invention include those derived from plant sources.

REFERENCES:
patent: 4588717 (1986-05-01), Mitchell
patent: 5106739 (1992-04-01), Comai et al.
patent: 5244887 (1993-09-01), Straub
patent: 5270041 (1993-12-01), Eugster et al.
patent: 5348886 (1994-09-01), Lee et al.
patent: 5378619 (1995-01-01), Rogers
patent: 5420034 (1995-05-01), Kridl et al.
patent: 5593874 (1997-01-01), Brown et al.
patent: 5608152 (1997-03-01), Kridl et al.
patent: 5633435 (1997-05-01), Barry et al.
patent: 5639790 (1997-06-01), Voelker et al.
patent: 5693507 (1997-12-01), Daniell et al.
patent: 6940003 (2005-09-01), Kinney et al.
patent: 0 120 515 (1990-02-01), None
patent: 0 255 378 (1994-04-01), None
patent: WO 96/38047 (1996-12-01), None
patent: WO 97/10328 (1997-03-01), None
patent: WO 97/42830 (1997-11-01), None
patent: WO 98/06405 (1998-02-01), None
patent: WO 98/06714 (1998-02-01), None
patent: WO 99/63096 (1999-12-01), None
AC003027; Federspiel N. et al. Gene F21M11.
TIGR: The Institute for Genomic Research database annotation for Gene F21M11.5.
Broun P. et al. Science vol. 282; Nov. 13, 1998, pp. 1315-1317.
Noiriel A. et al. European Journal of Biochemistry, 2004; vol. 271, pp. 3752-3764.
Altschul et al., “Basic local alignment search tool,”J. Mole. Biol., 215(3):403-410, 1990.
Bechtold et al., “InPlanta agrobacteriummediated gene transfer by infiltration of adultArabidopsis thalianaplants,”Life Sciences, 316(10):1194-1199, 1993.
Bent et al., “RPS2 ofArabidopsis thaliana: a leucine-rich repeat class of plant disease resistance gene,”Science, 265:1856-1860, 1994.
Cases et al., “ACAT-2, a second mammalian acyl-coA:cholesterol acyltransferase, its cloning, expression, and characterization,”J. Biol. Chem., 273(41):26755-26764, 1998.
Chang et al., “Acyl-coenzyme A: cholesterol acyltransferase,”Annual Review of Biochemistry, 66:613-638, 1997.
Chang et al., “Molecular cloning and functional expression of human acyl-coenzyme A: cholesterol acyltransferase cDNA in mutant chinese hamster ovary cells,”J.Biol. Chem., 268:20747-20755, 1993.
Chen et al., “Functional analysis of regulatory elements in a plant embryo-specific gene,”Proc. Natl. Acad. Sci. USA, 83(22):8560-8564, 1986.
Corazzi et al., “Tissue specific and light-regulated expression of a pea nuclear gene encoding the small subunit of ribulose-1,5-biophosphate carboxylase,”The EMBO Journal, 3(8):1671-1679, 1984.
Coulson, “High-performance searching of biosequence databases,”Trends in Biotechnology, 12(3):76-80, 1994.
Dahlqvist et al., “Phospholipid: diacyglycerol acyltransferase: an enzyme that catalizes the acyl-CoA-independent formation of triacylglycerol in yeast and plants,”Pro. Natl. Acad. Sci. USA, 97(12):6487-6492, 2000.
Depicker et al., “Nopaline synthase: transcript mapping and DNA sequence,”J. Mol. and Appl. Gene, 1(6):561-573, 1982.
Devereux et al., “A comprehensive set of sequence analysis programs for the VAX,”Nuc. Acids Res., pp. 387-395, 1983.
Ditta et al., “Broad host range DNA cloning system for gram-negative bacteria: construction of a gene bank of rhizobium meliloti,”Proc. Natl. Acad. Sci. USA, 77(12):7347-7351, 1980.
Fling et al., “Nucleotide sequence of the transposon Tn7 gene encoding an aminoglycoside-modifying enzyme, 3″(9)0-nucleotidyltransferase,”Nuc. Acids Res., 13(19):7095-7106, 1985.
Frentzen, “Acyltransferases from basic science to modified seed oils,”Fett/Lipid, 100(4/05):161-166, 1998.
Frohman et al., “Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer,”Proc. Natl. Acad. Sci. USA, 85(23):8998-9002, 1988.
Goodwin, “Biosynthesis of plant sterols and other triterpenoids,”Biosynthesis of Isoprenoid Compounds, 1:444-480, 1981.
Henikoff et al., “Amino acid substitution matrices from protein blocks,”Proc. Natl. Acad. Sci. USA, 89(22):10915-10919, 1992.
Hobbs et al., “Cloning of a cDNA encoding diacylglycerol acyltransferase fromArabidopsis thalianaand its functional expression,”Febs Letters, 452(3):145-149, 1999.
Holsters et al., “Transfection and transformation ofAgrobacterium tumefaciens,” Molec. Gen. Genet., 163:181-187, 1978.
Hood et al., “The hypervirulence ofAgrobacterium tumefaciensA281 is encoded in a region of pTiBo542 outside of T-DNA,”J. Bacter., 168(3):1291-1301, 1986.
Jouanin et al., “Localization and restriction maps of the replication origin regions of the plasmids ofAgrobacterium rhizogenesstrain A4,”Molec. Gen. Genet., 201:370-374, 1985.
Klein et al., “Transformation of microbes, plants and animals by particle bombardment,”Biotechnology, 10(3):286-291, 1992.
Kridl et al., “Isolation and characterization of an expressed napin gene from brassica rapa,”Seed Science Research, 1(4):209-219, 1991.
Leisy et al., “Expression of a rice glutelin promoter in transgenic tobacco,”Plant Mol. Bio., 14:41-50, 1989-1990.
McBride et al., “Improved binary vectors forAgrobacterium-mediated plant transformation,”Plant Mol. Bio., 14(2):269-276, 1990.
McLean et al., “Human lecithin-cholesterol acyltransferase gene: complete gene sequence and sites of expression,”Nuc. Acids Res., 14(23):9397-9406, 1986.
Morelli et al., “A short conserved sequence is involved in the light-inducibility of a gene encoding ribulose 1,5-biophosphate carboxylase small subunit of pea,”Nature, 315(6016):200- 204, 1985.
Napoli et al., “Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans,”The Plant Cell, 2:279-289, 1990.
Needleman et al., “A general method applicable to the search for similarities in the amino acid sequence of two proteins,”J. Molec. Biol., 48:443-453, 1970.
Nykiforuk et al., “Brassica napus putative diacylglycerol acyltransferase (DGATI) mRNA,” Accession No. XP002161573.
Oelkers et al., “A lecithin cholesterol acyltransferase-like gene mediates diacylglycerol esterification in yeast,”J. Biol. Chem., 275(21):15609-15612, 2000.
Radke et al., “Transformation and regeneration of brassica rapa usingAgrobacterium tumefaciens,” Plant Cell Reports, 11:499-505, 1992.
Radke et al., “Transformation of brassica napus L. usingAgrobacterium tumefaciens: developmentally regulated expression of a reintroduced napin gene,”Theor. Appl. Genet., 75:685-694, 1988.
Schwender et al., “Biosynthesis of sterols in green algae (Scenedesmus, chlorella) according to a novel, mevalonate-independent pathway,”Phys., Bio. and Mol. Bio. Plant Lipids, pp. 180-182, 1997.
Smith et al., “Antisense RNA inhibition of polygalacturonase gene expression in transgenic tomatoes,”Nature, 334(6184):725-726, 1988.
Smith et al., “Identification of common molecular subsequences,”J. Mole. Biol., 147(1):195-197, 1981.
Svab et al., “High-frequency plastid transformation in tobacco by selection for a chimeric aadA gene,”Proc. Natl. Acad. Sci. USA, 90(3):913-917, 1993.
Svab et al., “Stable transformation of plastids in higher plants,”P

Affiliated with

Also associated with

Rating

Plant sterol acyltransferases does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Plant sterol acyltransferases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Plant sterol acyltransferases will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4110409