Plant protein useful for treating tumors and HIV infection

Details Plant protein useful for treating tumors and HIV infection Plant protein useful for treating tumors and HIV infection

1994-07-21

1996-01-16

Furman, Keith C.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Plant proteins, e.g., derived from legumes, algae or...

530370, C07K 14415

Patent

active

054848890

ABSTRACT:
A protein, in particular MAP 30, obtainable from both the fruit and seeds of Momordica charantia or produced by recombinant means useful for treating tumors and HIV infections is disclosed. In treating HIV infections, the protein is administered alone or in conjunction with conventional AIDS therapies. Also provided are processes for purifying the protein, DNA sequences encoding the protein, and recombinant DNA methods for expressing the protein.

REFERENCES:
patent: 4795739 (1989-01-01), Lifson et al.
patent: 4883761 (1989-11-01), Keith et al.
patent: 5037960 (1991-08-01), Barbieri et al.
Li, S.S.L. 1980. Experientia 36:524-527.
Hird et al. 1990. Gener and Cancer, (D. Carney et al; Eds.), John Wiley & Sons Ltd; N.Y. pp. 184-189.
Altman et al. 1993. "AIDS Study Cart Doubt on Value of Hastened Drug Approval in U.S.", The New York Times, Apr. 6, p. C3.
Kubota et al. 1986. Biochimica et Biophysica Acta 871:101-106.
Stirpe et al. 1986. FEBS Letters 195:1-8.

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