Plant lecithin:cholesterol acyltransferases

Multicellular living organisms and unmodified parts thereof and – Plant – seedling – plant seed – or plant part – per se

Reexamination Certificate

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Details

C435S006120, C435S069100, C435S468000, C435S419000, C435S252300, C435S320100, C435S183000, C530S370000, C536S023600, C800S278000

Reexamination Certificate

active

11073512

ABSTRACT:
This invention relates to an isolated nucleic acid fragment encoding a plant lecithin:cholesterol acyltransferases. The invention also relates to the construction of a chimeric gene encoding all or a portion of the plant lecithin:cholesterol acyltransferases, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the plant lecithin:cholesterol acyltransferases in a transformed host cell.

REFERENCES:
patent: WO 98/46767 (1998-10-01), None
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Craig H. Warden et al., J. Biol. Chem., vol. 264(38):21573-21581, 1989, Tissue-specific Expression, Developmental Regulation, and Chromosomal mapping of the lecithin: cholesterol acyltransferase gene.
Yukio Murata et al., J. Lipid Res., vol. 37:1616-1622, 1996, Cloning of rabbit LCA cDNA:increase in LCAT mRNA abundance in the liver of cholesterol-fed rabbits.
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G. Meroni et al., Nucl. Acids Res., vol. 18(17):5308, Nucleotide sequence of the cDNA for lecithin:cholesterol acyltransferase (LCAT) from the rat.
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National Center for Biotechnology Information General Identifier No. 3935185, Dec. 1, 1998, P. Shinn et al., Genomic sequence forArabidopsis thalianaBAC F17L21.
Mitsuhisa Manabe et al., J. Lipid Res., vol. 28: 1206-1215, 1987, New substrate for determination of serum lecithin:cholesterol acyltransferase.
Sissel Rogne et al., The Isolation and Characterisation of a cDNA clone for Human lecithin:cholesterol Acyl Transferase and its Use to Analyze the Genes in Patients With LCA Deficiency and Fish Eye Disease, Biochemical and Biophysical Research Communications, vol. 148:161-169, 1987.

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