Multicellular living organisms and unmodified parts thereof and – Method of introducing a polynucleotide molecule into or...
Patent
1998-06-03
2000-12-05
Smith, Lynette R.F.
Multicellular living organisms and unmodified parts thereof and
Method of introducing a polynucleotide molecule into or...
800292, 800298, 800293, 800279, 800289, 800294, 283281, 283284, 283295, 283306, 283268, 283260, C12N 1587, A01H 900, A01H 1100, A01H 500, A01H 100
Patent
active
061569534
ABSTRACT:
The present invention provides for the identification and cloning of functional plant centromeres in Arabidopsis. This will permit construction of stably inherited plant artificial chromosomes (PLACs) which can serve as vectors for the construction of transgenic plant and animal cells. In addition, information on the structure and function of these regions will prove valuable in isolating additional centromeric and centromere related genetic elements and polypeptides from other species.
REFERENCES:
patent: 4889806 (1989-12-01), Olson et al.
patent: 5270201 (1993-12-01), Richards et al.
patent: 5288625 (1994-02-01), Hadlaczky
patent: 5695967 (1997-12-01), Van Brokkelen et al.
patent: 5712134 (1998-01-01), Hadlaczky
patent: 5721118 (1998-02-01), Scheffler
patent: 5869294 (1999-02-01), Harrington et al.
patent: 5891625 (1999-04-01), Hadlaczky
Abel et al., "Delay of disease development in transgenic plants that express the tobacco mosaic virus coat protein gene," Science 22:738-743, 1986.
Alfenito et al., "Molecular characterization of a maize B chromosome centric sequence," Genetics, 135:589-597, 1993.
Allshire, "Centromeres, checkpoints and chromatid cohesion," Genetics and Devel., 7:264-273, 1997.
Alonso-Blanco et al., "Development of an AFLP based linkage map of Ler, Col and Cvi Arabidopsis thaliana ecotypes and construction of a Ler/Cvi recombinant inbred line population," J. Plant, 14(2):259-271, 1998.
Baum et al., "The centromeric K-type repeat and the central core are together sufficient to establish a functional Schizosaccharomyces pombe centromere," Mol. Bio. Cell., 5:747-761, 1994.
Bell et al., "Assignment of 30 microsatellite loci to the linkage map of Arabidopsis," Genomics, 19:137-144, 1994.
Birchler, "Do these sequences make CENs yet?" Genome Res., 7:1035-1037, 1997.
Bloom, "The centromere frontier: Kinetochore components, microtubule-based motility, and the CEN-value paradox," Cell, 73:621-624, 1993.
Brown et al., "Mini-chromosomes derived from the human Y chromosome by telomere directed chromosome breakage," Proc. Natl. Acad. Sci. USA, (93):7125-7130, 1996.
Burke, et al., "Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors," Science, 236:806-812, 1987.
Capecchi, "High efficiency transformation by direct microinjection of DNA into cultured mammalian cells," Cell 22 (2):479-488, 1980.
Carbon et al., "Centromere structure and function in budding and fission yeasts," New Biologist, 2:10-19, 1990.
Chang et al., "Restriction fragment length polymorphism linkage map for Arabidopsis thaliana," Proc. Natl. Acad. Sci., USA, 85:6856-6860, 1988.
Choo, "Turning on the centromere," Nature Gene., 18:3-4, 1998.
Christou et al., "Stable transformation of soybean callus by DNA-coated gold particles," Plant Physiol., 87:671-674, 1988.
Chu, et al., "Separation of large DNA molecules by contour-clamped homogeneous electric fields," Science, 234:1582-1585, 1986.
Clarke et al., "Isolation of a yeast centromere and construction of functional small circular chromosomes," Nature, 287:504-509, 1980.
Clarke, et al., "Analysis of centromeric DNA in the fission yeast Schizosaccharomyces pombe," Proc. Natl. Acad. Sci. USA, 83:8253-8257, 1986.
Clarke, "Centromeres: proteins, protein complexes, and repeated domains at centromeres of simple eukaryotes," Genetics and Development, 8:212-218, 1998.
Copenhaver et al., "Assaying genome-wide recombination and centromere functions with Arabidopsis tetrads," Proc. Natl. Acad. Sci. USA, 95:247-252, 1998.
Depicker et al., "A negative selection scheme for tobacco protoplast-derived cells expressing the T-DNA gene 2," Plant Cell Reports, 7:63-66, 1988.
du Sart et al., "A functional neo-centromere formed through activation of a latent human centromere and consisting of non-alpha-satellite DNA," Nature Gene., 16:144-153, 1997.
Earnshaw et al., "Proteins of the inner and outer centromere of mitotic chromosomes," Genome, 31:541-552, 1989.
Earnshaw, "When is a centromere not a kinetochore?," J. Cell Sci., 99:1-4, 1991.
Fransz et al., "Cytogenetics for the model system arabidopsis thaliana," J. Plant, 13(6):867-876, 1998.
Frary et al., "Molecular mapping of the centromeres of tomato chromosomes 7 and 9," Mol. Gen. Genet., 250:295-304, 1996.
Fromm et al., "Expression of genes transferred into monocot and dicot plant cells by electroporation," Proc. Natl. Acad. Sci. USA 82(17):5824-5828, 1985.
Hadlaczky et al., "Centromere formation in mouse cells cotransformed with human DNA and a dominant marker gene," Proc. Natl. Acad. Sci. USA, 88:8106-8110, 1991.
Harrington et al., "Formation of de novo centromeres and construction of first-generation human artificial microchromosomes," Natures Genetics, 15:345-355, 1997.
Hegemann et al., "The centromere of budding yeast," Bioassays, 15(7):451-460, 1993.
Hwang et al., Identification and map position of YAC clones comprising one-third of the Arabidopsis genome, the Plant Journal, 1:367-374, 1991.
Ikeno et al., "Construction of YAC-based mammalian artificial chromosomes," Nature Biotech., 16:431-439, 1998.
Kaszas and Birchler, "Misdivision analysis of centromere structure in maize," J. EMBO, 15(19):5248-5256, 1996.
Klein et al., "High-velocity microprojectiles for delivering nucleic acids into living cells," Nature, 327:70-73, 1987.
Klein et al., "Stable genetic transformation of intact Nicotiana cells by the particle bombardment process," Proc. Nat'l Acad. Sci. USA, 85:8502-8505, 1988.
Konieczny et al., "A procedure for mapping Arabidopsis mutations using codominant ecotype-specific PCR-based markers," The Plant Journal, 4:403-410, 1993.
Koorneef, "Linkage map of Arabidopsis thaliana," J. Heredity, 74:265-272, 1983.
Koorneef, The use of telotrisomics for centromere mapping in Arabidopsis thaliana (L.) Heynh, Genetica, 62:33-40, 1983.
Koorneef et al., "Trisomics in Arabidopsis thaliana and the location of linkage groups," Genetica, 61:41-46, 1983.
Lorz et al., "Gene transfer to cereal cells mediated by protoplast transformation," Mol. Gen. Genet., 199:178, 1985.
Maluszynaska et al., "Molecular cytogenetics of the genus Arabidopsis: In situ localization of rDNA sites, chromosome numbers and diversity in centromeric heterochromatin," Annals Botany, 71:479-484, 1993.
Maluszynska and Heslop-Harrison, Localization of tandemly repeated DNA sequences in Arabidopsis thaliana, J. Plant, 1(2):159-166, 1991.
Martinez-Zapater et al., "A highly repeated DNA sequence in Arabidopsis thaliana," Mol. Gen. Genet., 204:417-423, 1986.
Mozo et al., "Construction and characterization of the IGF Arabidopis BAC library," Mol. Gen. Genet., 258:562-570, 1998.
Murphy and Karpen, "Localization of centromere function in a drosophila minichromosome," Cell, 82:599-609, 1995.
Murray et al., "Construction of artificial chromosomes in yeast," Nature, 305:189-193, 1983.
Perkins, "The detection of linkage in tetrad analysis," Genetics, 38, 187-197, 1953.
Potrykus et al., "Direct gene transfer to cells of a graminaceous monocot," Mol. Gen. Genet., 199:183, 1985.
Preuss et al., "Tetrad analysis possible in Arabidopsis with mutation of the Quartet (QRT) genes," Science, 264:1458, 1994.
Rattner, "The structure of the mammalian centromere," BioEssays, 13(2):51-55, 1991.
Richards et al,. "The centromere region of Arabidopsis thaliana chromosome 1 contains telomere-similar sequences," Nucleic Acids Research, 19(12):3351-3357, 1991.
Rosenfeld, "Human artificial chromosomes get real," Nature Genetics, 15:333-335, 1997.
Round et al., "Arabidopsis thaliana centromere region: genetic map positions and repetitive DNA structure," Gen. Res., 7:1045-1053, 1997.
Schmidt et al., "Physical map and organization of arabidopsis thaliana chromosome 4," Science, 270:480-483, 1995.
Singh et al., Centromere mapping and orientation of the molecular linkage map of rice (Oryza sativa L.), Proc. Natl. Acad. Sci. USA, 93:6163-6168, 1996.
Smythe, "Pollen clusters," Current Biology, 4:851-853, 1994.
Sun et al., "Human artificial episomal chromosomes for cloning large DNA fragments in human cells," Nature Genetics, 8:33-41, 1994.
Sun et al., "Molecular s
Copenhaver Gregory
Preuss Daphne
Smith Lynette R.F.
University of Chicago
Zaghmout Ousama M-Fail
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