Placental human neurokinin B precursor

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C436S518000

Reexamination Certificate

active

07947458

ABSTRACT:
Methods of diagnosing pregnancy induced hypertension or pre-eclampsia by the measurement of the production of neurokinin B, its precursor and fragments thereof are provided, as are kits for use in the methods. Treatments of the conditions and methods of preparing suitable medicaments are also provided as are antibodies and useful antigenic materials.

REFERENCES:
patent: 4665157 (1987-05-01), Wright
patent: 4742156 (1988-05-01), Wright
patent: 5328927 (1994-07-01), Lewis et al.
patent: 5331089 (1994-07-01), Curtis et al.
patent: 5344830 (1994-09-01), Mills et al.
patent: 5360820 (1994-11-01), Hagan et al.
patent: 5491140 (1996-02-01), Bruns, Jr. et al.
patent: 5612336 (1997-03-01), Lewis et al.
patent: 5846973 (1998-12-01), Gehlert et al.
patent: 5985606 (1999-11-01), Hillman et al.
patent: 6689566 (2004-02-01), Cantor et al.
patent: 2154116 (1996-01-01), None
patent: 0591040 (1994-04-01), None
patent: 0693489 (1996-01-01), None
patent: 9404494 (1994-03-01), None
Lucas et al. (Neuroscience 1992, vol. 51, p. 317-345).
Williams et al. (Infect & Immunity 2000 vol. 68, p. 2535-2545; include AntiJen search report.
Liljeqvist et al. (Abstract only, Journal Gen Virology 1998 vol. 79 (Pt 5), p. 1215-1224; include the attachment of AntiJen Epitope Search report.
Ngo et al. (1995) “The Protein Folding Problem and Tertiary Structure Prediction, Chapter 14: Computational Complexity Protein Structure Prediction, and the Levinthal Paradox” pp. 492-495 Editor by Merz et al.
Bork (2000) Genome Research 10:398-400.
Skolnick (2000) Trends in Biotech. 18: 34-39.
Smith et al. (1997) Nature Biotechnology 1999 15: 1222-1223.
Pennica et al (Proc. Nal. Acad. Sci, 95:14717-14722, 1998).
Haynes et al. (Electrophoresis, 19:1862-1871, 1998).
Konopka et al (PNAS 83:4049-52, 1986); Summer et al. Neurology 2006, vol. 66, p. 1067-1073).
Lewin (Genes VI (1997) Chapter 29, pp. 847-848) ; Gokman-Polar et al (Cancer Research 61:1375-1381, 2001).
Kangawa, et al., Neuromedin K: A Novel Mammalian Tachykinin Identified in Porcine Spinal Cord, Biochemical and Biophysical Research Communications, 1983, vol. 114, No. 2, pp. 533-540.
Mastrangelo, et al., The Rat Isolated Portal Vein: A Preparation Sensitive to Neurokinins, Particularly Neurokinin B, European Journal of Pharmacology, 1986, vol. 134, pp. 321-326.
D'Orléans-Juste, et al., Neurokinins Produce Selective Venoconstriction Via NK-3 Receptors in the Rat Mesenteric Vascular Bed, European Journal of Pharmacology, 1991, vol. 204, pp. 329-0334.
Garrett, et al., Pharmacological Properties of a Potent and Selective Nonpeptide Substance P Antagonist, Proc. Natl. Acad. Sci. USA, Nov. 1991, vol. 88, pp. 10208-10212.
Moussaoui, et al., Distrubution of Neurokinin B in Rat Spinal Cord and Peripheral Tissues: Comparison With Neurokinin A and Substance P and Effects of Neonatal Capsaicin Treatment, News Science, 1992, vol. 48, No. 4, pp. 969-978.
Henikoff, et al., Amino Acid Substitution Matrices From Protein Blocks, Proc. Natl. Acad. Sci. USA, Proc. Natl. Acad. Sci, USA, Nov. 1992, vol. 89, pp. 10915-10919.
Roccon, et al., Study of SR 142801, A New Potent Non-Peptide NK3Receptor Anatagonist on Cardiovascular Responses in Conscious Guinea-Pig, British Journal of Pharmacology, 1996, vol. 118, pp. 1095-1102.
Longmore, et al., Neurokinin-Receptor Antagonists: Pharmacological Tools and Therapeutic Drugs, Can. J. Physiol. Pharmacol., 1997, vol. 75, pp. 612-621.
Thompson, et al., Canine Intrinsic Cardiac Neurons Involved in Cardiac Regulation Possess NK1, NK2, and NK3Receptors, American Physicological Society, 1998, pp. R1683-R1689.
Page, et al., Excessive Placental Secretion of Neurokinin B During the Third Trimester Causes Pre-Eclampsia, Nature, Jun. 15, 2000, vol. 405, pp. 797-800.
Walker, Pre-Eclampsia, The Lancet, Oct. 7, 2000, vol. 356, pp. 1260-1265.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Placental human neurokinin B precursor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Placental human neurokinin B precursor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Placental human neurokinin B precursor will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2655893

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.