PLA.sub.2 inhibitors and their use for inhibition of intestinal

Details PLA.sub.2 inhibitors and their use for inhibition of intestinal PLA.sub.2 inhibitors and their use for inhibition of intestinal

1996-03-04

1999-10-19

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548251, 548557, 548577, 560205, 564104, 564106, 564204, 564209, 570127, 570184, A61K 3141, C07D25706

Patent

active

059689633

ABSTRACT:
Certain compounds have been synthesized and found to be effective inhibitors of phospholipase A.sub.2 (PLA.sub.2), and thereby useful in the treatment of intestinal cholesterol absorption and the disease states arising therefrom, such as hypercholesterolemia and coronary artery disease.

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