Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1994-07-01
1996-04-02
Brust, Joseph Paul
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514113, 514128, 558197, A61K 3166
Patent
active
055040730
ABSTRACT:
Certain compounds have been synthesized and found to be effective inhibitors of phospholipase A.sub.2 (PLA.sub.2), and thereby useful in the treatment of intestinal cholesterol absorption and the disease states arising therefrom, such as hypercholesterolemia and coronary artery disease.
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"Inhibition of intestinal absorption of endogenous cholesterol is not sufficient to lower plasma cholesterol in hamsters and rats", H. Lengsfeld et al. date not available!.
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Ashbrook Charles W.
Atkins Michael J.
Brust Joseph Paul
Warner-Lambert & Company
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