Measuring and testing – Instrument proving or calibrating – Volume of flow – speed of flow – volume rate of flow – or mass...
Patent
1993-03-11
1996-01-09
Noland, Thomas P.
Measuring and testing
Instrument proving or calibrating
Volume of flow, speed of flow, volume rate of flow, or mass...
7386414, 7386418, G01N 114, B01L 302, G01F 2500
Patent
active
054819008
ABSTRACT:
The present invention relates to a method for defining an error compensation for the difference between a desired quantity of liquid and the quantity of liquid actually drawn into a disposable pipette tip mounted on a plunger-operated pipette, comprising adjusting arrangement (5,6,36,50) for adjusting the stroke of a plunger (9,10) and an indicator 51 for the desired quantity of liquid, wherein the relation of the stroke of the plunger with respect to the quantity of liquid indicated is defined by a plunger-correcting factor, the pipette tip comprising an opening communicating with an operating portion to be filled with a desired quantity of liquid, and a mounting opening for disposably connecting to the plunger-operated pipette, wherein a dead volume is defined between the plunger and the opening communicating with operating portion, and to a pipette system comprising a plunger-operated pipette and a pipette tip. According to the invention, the quantity of liquid to be taken in shall be defined more accurately over the total operating range of the plunger movement. For this, a number of parameters such as the plunger correcting factor, the longitudinal internal contour of the pipette tip and the dead volume are mutually tuned for each particular quantity of liquid to be taken in resulting in a predetermined error of the quantity of liquid indicated.
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Labsystems, Finland Instructions For Use Finnpipette Digital, pp. 1-7 published by Sep. 1994.
Eppendorf, Germany published by Apr. 1986 Comforpette 4700, Varipette 4710 und Comfortip cristal (3 pages).
Eppendorf-Netheler-Hinz GmbH
Noland Thomas P.
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