Piperidylmethyl-substituted chroman derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514320, 546187, 546196, 546206, A61K 31445, C07D40506, C07D40514

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active

053267710

ABSTRACT:
Piperidylmethyl-substituted chroman derivatives can be prepared by first reducing corresponding chromancarboxylic acid derivatives, if appropriate with prior activation, with the cyclic amines and then reducing the carbonyl group, or by reacting chromanmethyl compounds directly with the cyclic amines. The substituted piperidylmethyl-substituted chroman derivatives can be employed as active compounds in medicaments, in particular for the treatment of diseases of the central-nervous system.

REFERENCES:
patent: 3759927 (1973-09-01), Huebner
patent: 3826835 (1974-07-01), Huebner
patent: 3845060 (1974-10-01), Huebner
patent: 4376123 (1983-03-01), Hausberg et al.
patent: 4745114 (1988-05-01), Elliott et al.
patent: 4957928 (1990-09-01), Frostl et al.
patent: 5112855 (1992-05-01), Frostl et al.
patent: 5137901 (1992-08-01), Junge et al.
J. Med. Chem. 22 (6) 539-544, 1986.
Eur. J. Med. Chem. 22 (6) 539-544, 1987.
Farmaco, Ed. Sci. 42 (11) 805-813, 1989.
Aldrichimica Acta 18, 25, 1985.
Still et al, J. Org. Chem. 43, 2923, 1978.

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