Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-01-23
2009-10-13
Desai, Rita J (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C514S317000
Reexamination Certificate
active
07601844
ABSTRACT:
The present application describes substituted piperidinyl modulators of MIP-1α or CCR-1 or stereoisomers or pharmaceutically acceptable salts thereof. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and transplant rejection using said modulators are disclosed.
REFERENCES:
patent: 5492920 (1996-02-01), Chen et al.
patent: 5847148 (1998-12-01), Jacobsen et al.
patent: 6194448 (2001-02-01), Biediger et al.
patent: 6344449 (2002-02-01), Rudolf et al.
patent: 6391865 (2002-05-01), Baroudy et al.
patent: 6638950 (2003-10-01), Duncia et al.
patent: 6846836 (2005-01-01), Hamann et al.
patent: 2003/0162764 (2003-08-01), Castelhano et al.
patent: 2003/0229067 (2003-12-01), Castelhano et al.
patent: 2004/0006067 (2004-01-01), Fotsch et al.
patent: 2007/0123509 (2007-05-01), Cezanne et al.
patent: 2007/0179148 (2007-08-01), Carter et al.
patent: 4243858 (1994-06-01), None
patent: 0838460 (1998-04-01), None
patent: 2001-354657 (2000-12-01), None
patent: WO 92/15304 (1992-09-01), None
patent: WO 94/25437 (1994-11-01), None
patent: WO 95/34311 (1995-12-01), None
patent: WO 97/38665 (1997-10-01), None
patent: WO 98/17625 (1998-04-01), None
patent: WO 99/08697 (1999-02-01), None
patent: WO 99/08699 (1999-02-01), None
patent: WO 00/74679 (2000-12-01), None
patent: WO 02/059117 (2002-08-01), None
patent: WO 02/070511 (2002-09-01), None
patent: WO 02/092582 (2002-11-01), None
patent: WO 03/007949 (2003-01-01), None
patent: WO 03/009847 (2003-02-01), None
patent: WO 03/022835 (2003-03-01), None
patent: WO 03/092688 (2003-11-01), None
patent: WO 2004/037796 (2004-05-01), None
patent: WO 2004/076418 (2004-09-01), None
patent: WO 2004/113323 (2004-12-01), None
patent: WO 2005/003127 (2005-01-01), None
patent: WO 2005/056015 (2005-06-01), None
patent: WO 2005/084672 (2005-09-01), None
patent: WO 2005/118579 (2005-12-01), None
patent: WO 2006/013073 (2006-02-01), None
F.Z. Dorwald “Side Reactions in Organic Synthesis: A Guide to Successful Synthesis Design” 2005, Wiley-VCH Verlag GmbH & Co. KGaA, Wienheim.
Baraldi, P. et al., “Synthesis and biological activity of N-arylpiperazine-modified analogues of KN-62, a potent anagonist of the purinergic P2X7receptor”, J. Med. Chem., vol. 46, pp. 1318-1320 (2003).
Carson, K. et al., “CCR1 Antagonists”, Annual Reports in Medicinal Chemistry, vol. 39, pp. 149-158 (2004).
Lang, L. et al., (Database Beilstein, Beilstein Institute for Organic Chemistry, BRN#: 8854794), J. Labelled Compd. Radiopharm., vol. 44, pp. S21-S23 (2001).
Oshiro, Y. et al., “Novel cerebroprotective agents with central nervous system stimulating activity. 2. Synthesis and pharmacology of the 1-(acylamino)-7-hydroxyindan derivatives”, J. Med. Chem., vol. 34, No. 7, pp. 2014-2023 (1991).
Pessoa-Mahana, H. et al., “Synthesis of 4-arylpiperazine derivatives of moclobemide: Potential antidepressants with a dual mode of action”, Synthetic Communications, vol. 34, No. 14, pp. 2513-2521 (2004).
Richardson, T. et al., “Synthesis and structure -activity relationships of novel arylpiperazines as potent and selective agonists of the melanocortin subtype-4 receptor”, J. Med. Chem., vol. 47, pp. 744-755 (2004).
Tiwari, M., (Database Beilstein, Beilstein Institute for Organic Chemistry BRN#: 943608, 944316), J. Indian Chem. Soc., vol. 53, pp. 310-311 (1976).
Carter Percy H.
Cavallaro Cullen L.
Dodd Dharmpal S.
Duncia John V.
Gardner Daniel S.
Bogie Terence J.
Bristol--Myers Squibb Company
Desai Rita J
Korsen Elliott
Mabry John
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