Drug – bio-affecting and body treating compositions – Dentifrices – Ammonia – amine – or derivative thereof
Patent
1977-03-11
1978-10-10
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Dentifrices
Ammonia, amine, or derivative thereof
26029366, C07D22120, A61K 31445
Patent
active
041197119
ABSTRACT:
Novel spiro 1-(hydroxyalkyl)-piperidino derivatives and acid addition salts thereof, useful in the prevention and treatment of dental caries and periodontitis, are disclosed. Methods of preparing said derivatives, orally acceptable compositions containing said compounds, and a method of treatment therewith are also disclosed.
REFERENCES:
patent: 3256276 (1966-06-01), Grogan et al.
patent: 3256277 (1966-06-01), Rice et al.
patent: 3432499 (1969-03-01), Rice et al.
Naylor et al., "Dental Plaque", (1969), pp. 41-45. (A Symposium held in the University of Dundee, Sep. 1969).
Atistrom et al., "J. Peridont. Rev.", vol. 6, pp. 110-114 (1971).
Egelberg, "Odont. Rev.", vol. 16, No. 1, (1965), pp. 31-41.
Pigman et al., "J. Dent. Res.", (1952), pp. 627-633.
Hernestam Sven Erik Harry
Nilsson Nils Arne
Nordvi Curt Harry
Willard Lars-Olof
AB Ferrosan
Bond Robert T.
Jiles Henry R.
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