Piperidinesulfonylurea derivatives

Details Piperidinesulfonylurea derivatives Piperidinesulfonylurea derivatives

1975-07-25

1976-10-19

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

A61K 3147

Patent

active

039871720

ABSTRACT:
A series of novel 1-piperidinesulfonylurea compounds derived from a nitrogen-containing monocarboxylic acid have been prepared by reacting an appropriate sulfamide with an organic isocyanate or a trisubstituted urea equivalent thereof. The sulfamylureas so obtained are useful in therapy as oral hypoglycemic agents. Typical members include those compounds derived from 2-methoxynicotinic acid, of which 1-(bicyclo[2.2.1]hept-5-en-2-yl-endo-methyl)-3-{4-[2-(2-methoxynicotinamid o)ethyl]-1-piperidinesulfonyl}-urea is a most preferred embodiment.

REFERENCES:
patent: 3847939 (1974-11-01), Weber et al.

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