Piperidine-substituted indoles-or heteroderivatives thereof

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

active

07544806

ABSTRACT:
Accordingly, one object of the present invention are novel piperidine-substituted indoles- or heteroderivatives thereof of the formula 1:wherein R1, R5, R6, A, B, D-E, X-W-V, Y, i, j, n and m are defined as below.Another object of the present invention is to provide agonists or antagonists of CCR-3, or pharmaceutically acceptable salts thereof, more particularly to provide pharmaceutical compositions comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of at least one of the compounds of the present invention or a pharmaceutically acceptable salt thereof.

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F. Z. Dorwald “Side Reactions in Organic Synthesis: A Guide to Successful Synthesis Design” 2005 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

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