Piperidine derivatives useful as modulators of chemokine...

Details Piperidine derivatives useful as modulators of chemokine... Piperidine derivatives useful as modulators of chemokine...

2007-12-11

2007-12-11

Chang, Celia (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S235500, C544S129000, C546S187000

Reexamination Certificate

active

10480625

ABSTRACT:
The invention provides a compound of formula (I), wherein: T is C(O) or S(O)2; W is C(O) or S(O)2; X is CH2, O or NH; Y is CR5or N; R1is optionally substituted aryl or optionally substituted heterocyclyl; R2is hydrogen or C1-6alkyl; R3is hydrogen or optionally substituted C1-6alkyl; and R4is alkyl, optionally substituted aryl, optionally substituted aralkyl or optionally substituted heterocyclyl; that are modulators of chemokine (especially CCR3) activity and are especially useful for treating asthma and/or rhinitis

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