Piperidine derivatives, their preparation and pharmaceutical com

Details Piperidine derivatives, their preparation and pharmaceutical com Piperidine derivatives, their preparation and pharmaceutical com

1983-06-14

1985-07-16

Milestone, Norma S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546205, 546216, 546221, 546197, 514327, 514321, A61K 31445, C07D21146

Patent

active

045297304

ABSTRACT:
A piperidine derivative of the formula: ##STR1## wherein R represents a hydrogen atom, a (C.sub.1-4)alkyl, hydroxy(C.sub.1-4)alkyl, (C.sub.1-4)alkoxycarbonyl or benzyl radical, or a benzyl radical carrying a substituent selected from halogen atoms and (C.sub.1-4)alkoxy radicals, or the phenethyl or 3-phenylpropyl radical, and X represents one or more hydrogen or halogen atoms or (C.sub.1-4)alkyl, (C.sub.1-4)alkoxy, trifluoromethyl or methylenedioxy radicals, or alternatively X forms with the phenyl nucleus a naphthyl radical, with the proviso that when R represents a hydrogen atom X is other than a hydrogen atom, are new compounds useful in therapy and, more particularly, as antidepressants.

REFERENCES:
patent: 2716122 (1955-08-01), Levy et al.
patent: 2751388 (1956-06-01), Levy
patent: 2831862 (1958-04-01), Biel
patent: 2974146 (1961-03-01), Biel
patent: 3260723 (1966-07-01), L'Italien et al.
patent: 3542794 (1970-11-01), Helsley
patent: 3743645 (1973-07-01), Helsley

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