Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1999-02-22
2000-04-18
Ramsuer, Robert W.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
544129, 544360, 546206, C07D21142
Patent
active
060517123
ABSTRACT:
Novel piperidine derivatives, their manufacture and use as medicaments, are disclosed. The invention is concerned with the novel piperidine derivatives of general formula I ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, Q, X, Z, m and n are as described herein.
REFERENCES:
patent: 4007196 (1977-02-01), Christenson et al.
patent: 4320137 (1982-03-01), Paioni
patent: 5378712 (1995-01-01), Alig et al.
patent: 5545658 (1996-08-01), Alig et al.
Beckett et al., Journal of Medicinal and Pharma. Chem., vol. 1(1), 37-58 (1959).
Jaeger et al., Org. Chem. 30(3): 740-744 (1965).
Boger et al., J. Med. Chem., 28:1779-1790 (1985).
Ferles et al., Coll. Czechoslov. Chem. Commun. 35:2802-2809 (1970).
Lounasmaa et al., Tetrahedron Letters, 29:2509 (1974).
Kovacs et al., Helv. Chem. Acta vol. XXXCII, 802 (1954).
Ito et al., Chem. Pharm. Bull. 22(9): 2131 (1974).
Arslan et al., J. Org. Chem. 58:2260 (1993).
Gribble et al,. Synth. Commun. 17:377 (1987).
Mancuso et al., J. Org. Chem. 43:2480 (1978).
Cardwell et al., J. Am. Chem. Soc. 110:2242 (1988).
Moser et al., Helv. Chim. Acta 69:1224 (1986).
Fischli et al., Hypertension 18(1):22-31 (1991).
Pals et al., Hypertension 8:1105-1112 (1986).
Clozel et al., Hypertension 22(1):9-17 (1993).
Dellaria et al., J. Med. chem. 30:2137-2144 (1987).
Kokubu et al, Biochem. Biophys. Res. Commun. 118:929-933 (1984).
Willcocks et al., J. of Labelled Cmpds and Radiopharm., vol. 33, No. 8 783-794 (1993).
Binggeli Alfred
Breu Volker
Bur Daniel
Fischli Walter
Guller Rolf
Epstein William H.
Hoffmann-La Roche Inc.
Johnston George W.
Parise John P.
Ramsuer Robert W.
LandOfFree
Piperidine derivatives having renin inhibiting activity does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Piperidine derivatives having renin inhibiting activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Piperidine derivatives having renin inhibiting activity will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2337204