Piperidine derivatives as antihistaminics

Details Piperidine derivatives as antihistaminics Piperidine derivatives as antihistaminics

1990-02-28

1991-09-24

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546198, C07D40112

Patent

active

050515101

ABSTRACT:
New antihistaminic piperidine derivatives of general structural formula I e prepared by reacting 4-piperidinealkylamines with carboxylic acids or their active derivatives, such as lower-alkyl esters or the acid chlorides.
The obtained new piperidine carboxamide compounds show potent antihistaminic activity as specific antagonists of histamine H1-receptors. ##STR1##

REFERENCES:
patent: 4621097 (1986-11-01), Butler et al.

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