Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1985-10-15
1987-07-14
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514318, 514322, 544285, 544250, 546192, 546193, 546194, 546199, 546212, 546237, 548305, A61K 31505, C07D40104
Patent
active
046802967
ABSTRACT:
Piperidine derivatives which are compounds of formula (I) ##STR1## wherein Ar.sub.1 and Ar.sub.2 independently represent a phenyl group optionally substituted by a halogen atom, a thienyl group or a pyridinyl group, A represents an alkylene group of 2 to 6 carbon atoms, X represents a CO group or a bond, R.sub.1 represents a hydrogen atom or an alkyl group of 1 to 4 carbon atoms, either R.sub.2 represents a hydrogen atom and R.sub.3 represents a hydrogen atom or a hydroxy group, or R.sub.2 and R.sub.3 together represent a bond, and R.sub.4 represents a hydrogen or halogen atom, or pharmaceutically acceptable acid addition salts thereof are useful as antiallergics and antipruritics.
REFERENCES:
patent: 3879393 (1975-04-01), Havera
patent: 4016166 (1977-04-01), Noda et al.
patent: 4588722 (1986-05-01), Janssens et al.
Binet Jean
Dewitte Elisabeth
Manoury Philippe
Hollrah Glennon H.
Synthelabo
Turnipseed James H.
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