Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-05-23
1995-12-26
Gupta, Yogenbra N.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514217, 514314, 5142338, 546166, 546169, 546170, 546187, 546189, 546198, 546201, 544105, 544284, 540586, A61K 31445, C07D40104
Patent
active
054788455
ABSTRACT:
Piperidine derivatives of formula ##STR1## wherein A is straight or branched alkyl, alkoxy-alkyl, or alkenyl; X is O or NH; Y is O, S, NH, NCN, or N-alkyl; R.sup.1 is 6-fluoro-1,2-benzisoxazol-3-yl, 6-fluoro-1H-indazol-3-yl, or 6-fluoro-1-methyl-1H-indazol-3-yl; R.sup.2 is alkyl or phenyl; and R.sup.3 is phenyl optionally substituted, or R.sup.3 is ##STR2## wherein Z represents a 5- or 6-membered heterocyclic ring; or R.sup.2 and R.sup.3 together with the nitrogen atom form a fused heterocyclic ring system; or pharmaceutically acceptable salts thereof are useful in the treatment of indications related to the CNS-system, cardiovascular system or to gastrointestinal disorders.
REFERENCES:
patent: 5001134 (1991-03-01), Ferrand et al.
patent: 5100902 (1992-03-01), Peglion et al.
patent: 5134147 (1992-07-01), Peglion et al.
Yevich et al., J. Med. Chem., vol. 29, pp. 359-369 (1986).
Gronvald Frederik C.
Hansen John B.
Mogensen John P.
Gupta Yogenbra N.
Lambiris Elias J.
Novo Nordisk A S
Zelson Steve T.
LandOfFree
Piperidine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Piperidine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Piperidine derivatives will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1369490