Piperidine derivative

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D21158, A61K 31445

Patent

active

050268589

ABSTRACT:
This invention relates to substituted benzoic acid amides of N-substituted piperidine and to pharmaceutical compositions thereof. The pharmaceutical compositions have served therapeutic uses, including treating nausea and vomiting, gastrointestinal disorders, and a variety of conditions affecting the central nervous system. The invention also relates to methods of preparing piperidine derivatives.

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B. Costall et al., European Journal of Pharmacology, vol. 18, (1972), pp. 95-106.
Nils-Erik Anden et al., J. Pharm. Pharmac., (1973), vol. 25, pp. 346-348.
G. Bartholini, J. Pharm. Pharmac., (1976), vol. 28, pp. 429-433.
F. Sulser et al., Psychopharmacology, (1978), pp. 943-954.
Brenda Costall et al., European Journal of Pharmacology, (1980), vol. 66, pp. 207-215.
J. Prieto et al., J. Pharm. Pharmac., (1977), vol. 29, pp. 147-152.

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