Piperidine containing aminobornic acids

Details Piperidine containing aminobornic acids Piperidine containing aminobornic acids

1995-03-24

1998-03-24

Dean, Ralph H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514 20, 514 18, 514 89, C07F 502, C07F 504, C07F 505

Patent

active

057314390

ABSTRACT:
The present invention relates generally to .alpha.-aminoboronic acids and corresponding peptide analogs in which the .alpha.-carbon is substituted with an optionally functionalized piperidine containing alkyl group. These compounds are useful as inhibitors of trypsin-like serine protease enzymes.

REFERENCES:
patent: 4499082 (1985-02-01), Shenvi et al.
patent: 4963655 (1990-10-01), Kinder et al.
patent: 5187157 (1993-02-01), Kettner et al.
patent: 5260307 (1993-11-01), Ackerman et al.
patent: 5442100 (1995-08-01), Bjorkquist et al.
patent: 5532232 (1996-07-01), Ackermann et al.

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