Piperidine compounds useful to treat cerebrovascular diseases

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514314, 514315, 514319, 514327, 514329, 540597, 540604, 540605, 540607, 540610, 546168, 546175, 546193, 546194, 546205, 546206, 546221, 546223, 546225, 546242, 546244, 546245, A61K 31445, C07D21146, C07D21158, C07D40102

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051964392

ABSTRACT:
A cyclic amine is defined by the formula: ##STR1## in which A is naphthyl, phenyl, quinolyl or alkyl, X is a group containing carbonyl, n is 2 or 3 and B is alkyl, halogen, phenyl or --YZ, Y being --O--, --CO-- or --NH--, Z being phenyl, naphthyl, pyridyl, alkyl or cycloalkyl. It is useful to treat mental symptoms associated with a cerebrovascular disease.

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Journal of Medicinal Chemistry, vol. 13, No. 1, (1970), pp. 1-6, Duncan et al.
Arzneimittelforschung, vol. 39, No. 4, (1989), pp. 445-450, Kaneko et al.
Japanese-United States Congress of Pharmaceutical Sciences, Dec. 2-7, 1987, p. 159.

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