Piperidine compounds and their use as antiarrhythmic agents

Details Piperidine compounds and their use as antiarrhythmic agents Piperidine compounds and their use as antiarrhythmic agents

1991-10-04

1993-07-20

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546203, A61K 31445, C07D21170

Patent

active

052294005

ABSTRACT:
A piperidine derivative of general formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## wherein ##STR2## is any of several specified aromatic-containing groups; X is selected from one of several hetero atom-containing groups or C.sub.2 alkylene or a cyano-containing group; and Q is phenyl, cyclohexyl, piperidinyl, tetrahydropyranyl, pyridyl, pyrrolyl, N-methylpyrrolyl, thienyl, furyl, 1-hexyl, or cyano; from 1 to 3 hydrogen atoms in Q may be independently substituted by alkyl of from 1 to 3 carbon atoms, perfluoroalkyl of from 1 to 3 carbon atoms, acylamino of from 1 to 6 carbon atoms, perfluoroacylamino of from 1 to 3 carbon atoms, alkoxy of from 1 to 3 carbon atoms, alkanesulfonylamino of from 1 to 3 carbon atoms, perfluoroalkanesulfonylamino of from 1 to 3 carbon atoms, acetoxy of from 1 to 3 carbon atoms, aminocarbonyl, aminosulfonyl, fluoro, chloro, cyano, hydroxy, nitro, amino, imidazolylmethyl, cinnamoylamino, p-fluorobenzoyl, cyanomethyl, cyanoethyl, methoxyacetoxy, alkoxycarbonyl of from 1 to 3 carbon atoms; 1 is an integer of from 0 to 1; m is an integer of from 0 to 1; n is an integer of from 0 to 6.
The derivatives are useful as antiarrhythmic agents.

REFERENCES:
Chemical Abstracts, vol. 106, No. 25, Jun. 22, 1987, p. 645, No. 213767z, H. Sugimoto, et al.,
Hackh Chemical Dictionary, 1969, p. 160.

Affiliated with

Also associated with

Rating

Piperidine compounds and their use as antiarrhythmic agents does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Piperidine compounds and their use as antiarrhythmic agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Piperidine compounds and their use as antiarrhythmic agents will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1760824