Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-12-11
1992-06-30
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514320, 514324, 546192, 546196, 546202, 546216, 546217, A61K 31445, C07D21154
Patent
active
051263564
ABSTRACT:
The compounds disclosed are 1-R'-4-RS-piperidines in which R' and R, which are different, may each represent: (1) (alkoxybenzyl)-alkyl or -alkenyl, or (2) (optionally-substituted chromanyl-, thiochromanyl-, chromenyl- or thiochromenyl)-alkyl or -alkenyl. The compounds are useful in the treatment of disorders associated with tissue ischaemia and of peripheral vascular disorders or in the treatment of disorders in which lipid peroxidation plays an initiating and/or aggravating role. A typical disclosed compound is: 4-(2,3,4-tirmethoxybenzylthio)-1-(3,5-di- tert-butyl-4-hydroxybenzyl)piperidine. ,3,4-trimethoxybenzylthio)-1-(3,5-di-tert-butyl-4-hydroxybenzyl)piperidine .
REFERENCES:
patent: 4529730 (1985-07-01), Schneider et al.
Benaud De La Faverie J. F.
Bidouard Jean-Pierre
Iliou Jean-Pierre
Lenaers Albert
Lombet Alain
Adir et Compagnie
Hollrah Glennon H.
Hueschen Gordon W.
Kumar Shailendra
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