Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-11-13
2007-11-13
Wilson, James O. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S255010, C514S255050, C544S358000, C544S360000, C544S367000, C544S372000, C544S374000, C544S386000
Reexamination Certificate
active
10516808
ABSTRACT:
The invention relates to substituted 1-piperazinylacylpiperidine derivatives of general formula (I)in which:n is 1 or 2;R1represents a halogen atom; a trifluoromethyl radical; a (C1-C4) alkyl; a (C1-C4)alkoxy; a trifluoromethoxy radical;R2represents a hydrogen atom or a halogen atom;R3represents a hydrogen atom; a group —OR5; a group —CH2OR5; a group —NR6R7; a group —NR8COR9; a group —NR8CONR10R11; a group —CH2NR12R13; a group —CH2NR8CONR14R15; a (C1-C4)alkoxycarbonyl; a group —CONR16R17;or else R3constitutes a double bond between the carbon atom to which it is attached and the adjacent carbon atom of the piperidine ring;R4represents the aromatic group 1,3-thiazol-2-yl of formula:Preparation process and therapeutic application.
REFERENCES:
patent: 4994455 (1991-02-01), Welch, Jr.
patent: 2003/0083347 (2003-05-01), Baroni et al.
patent: 2 803 593 (2001-07-01), None
patent: WO 00 69829 (2000-11-01), None
West, Anthony R., Solid State Chemistry and Its Applications, Wiley, New York, 1988, 358.
Venters, H.D., et al., Tumor Necrosis Factor-α Induces Neuronal Death by Silencing Survival Signals Generated by the Type I Insulin-like Growth Factor Receptor, Annals New York Academy of Sciences, 917(1) 210-220 (2000).
Bono Françoise
Bosch Michaël
Dos Santos Victor
Herbert Jean-Marc
Nisato Dino
Gupta Balaram
Leeser Erich
Sanofi-Aventis
Wilson James O.
LandOfFree
Piperazinylacylpiperidine derivatives, their preparation and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Piperazinylacylpiperidine derivatives, their preparation and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Piperazinylacylpiperidine derivatives, their preparation and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3867778