Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1998-07-16
2000-11-28
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544278, 544280, A61K 31519, C07D48704, C07D49804, C07D51304
Patent
active
061536148
ABSTRACT:
Compounds of Formula I ##STR1## and II and their pharmaceutically acceptable, salts, esters and prodrugs thereof are selective alpha-1D adrenoceptor anatagonists and may be useful for treating disease states, such as benign prostatic hyperplasia, detrusor insatbility, and incontinence.
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patent: 5521181 (1996-05-01), Meyer et al.
Romeo, G., et al., "Heterocyclic Systems Containing the Pyrimido-2,4-Dione Ring as Selective Ligands for the .alpha..sub.1 -Adrenoceptors", IL Farmaco, 50(6):471-477 (1995).
Russell, R. K., et al., "Thiophene Systems. 9. Thienopyrimidinedione Derivatives as Potential Antihypertensive Agents", J. Med. Chem., 31:1786-1793 (1988).
Carroll William A.
Meyer Michael D.
Abbott Laboratories
Raymond Richard L.
Ward Michael J.
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