Piperazinyl derivatives of purines and isosteres thereof as hypo

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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544255, 544276, 544277, 544362, A61K 3152, C07D47318, C07D47334, C07D47104

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active

050575171

ABSTRACT:
There are disclosed certain 6-piperazinopurines and heteroaromatic derivatives thereof which have oral hypoglycemic acitivity and with such ability to lower blood sugar are useful in the treatment of type II diabetes and/or obesity with associated insulin resistance. Processes for the preparation of such compounds and compositions containing such compounds as the active ingredient thereof are also disclosed.

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