Piperazinophenyl- and piperazinophenyloxycarboxylic acid derivat

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514255, 544360, 544392, A61K 31495, C07D40104, C07D295135

Patent

active

058439480

ABSTRACT:
Compounds having fibrinogen receptor-antagonistic activity, of the general formula I ##STR1## in which Z is oxygen or a methylene group,

REFERENCES:
patent: 5273982 (1993-12-01), Alig et al.
patent: 5442064 (1995-08-01), Pieper et al.
patent: 5563268 (1996-10-01), Linz et al.
Eldred et al., "Orally Active Non-Peptide Fibrinogen Receptor GpIIb/IIIa) Antangonists . . . " J. Med. Chem., vol. 37:3882-85 1994).
Judkins et al., "A Versatile Synthesis of Amidines From Nitriles Via Amidoximes", Synthetic Commun., vol. 26(23):4351-67 (1996).

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