Piperazino-pyrimidines and their use as spasmolytic agents

Details Piperazino-pyrimidines and their use as spasmolytic agents Piperazino-pyrimidines and their use as spasmolytic agents

1977-02-28

1979-09-04

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544295, 544298, 544320, 544332, 544121, A61K 31505, C07D40304

Patent

active

041668529

ABSTRACT:
The compounds of the formula: ##STR1## in which R represents a methyl or methylthio group, X represents a halogen atom or an alkoxy group containing 1 to 5 carbon atoms, Y represents an acylamino group or a substituted or unsubstituted amino group, Z represents a hydrogen atom or a methyl, ethyl, hdroxyethyl or phenyl group, with the exception of 2-methylamino-4-N-methylpiperazino-5-methylthio-6-chloro-pyrimidine; process for their preparation: medicaments comprising such compounds or salts thereof and with pharmaceutically acceptable acids and the use of such compounds or salts in the treatment of human beings.

REFERENCES:
patent: 2985657 (1967-07-01), Janssen
patent: 3060183 (1962-10-01), Clark et al.
patent: 3299067 (1967-01-01), Regnier et al.
patent: 3585193 (1971-06-01), Regnier
patent: 3843656 (1974-10-01), Obellaine

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