Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1979-04-05
1981-03-31
Sutto, Anton H.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544391, 544398, 544402, A61K 31495, C07D29508
Patent
active
042593344
ABSTRACT:
The invention relates to compounds having the formula: ##STR1## in which: the substituents R.sub.1, R.sub.2 and R.sub.3 represent independently from each other a hydrogen atom, a halogen atom, a trifluoromethyl radical, a saturated or unsaturated straight- or branched-chain C.sub.1-6 alkyl radical, a C.sub.1-6 alkoxy radical the alkyl moiety of which may be saturated or unsaturated and straight- or branched-chained, a benzyloxy radical or a hydroxy radical;
the substituents R.sub.5, R.sub.6 and R.sub.7 represent independently from each other a hydrogen atom, a halogen atom, a trifluoromethyl radical, a straight- or branched-chain saturated or unsaturated C.sub.1-6 alkyl radical, a C.sub.1-6 alkoxy radical the alkyl moiety of which may be saturated or unsaturated and straight- or branched-chained, or a hydroxy radical;
the substituent R.sub.4 represents a hydrogen atom, a C.sub.1-6 alkyl radical or a hydroxy radical,
m and n represent independently a number equal to 0, 1 or 2,
X represents an oxygen atom, a sulfur atom or a single bond, and their pharmaceutically acceptable acid addition salts.
These compounds are therapeutically useful for the control of the cardiovascular system.
REFERENCES:
patent: 3793322 (1974-02-01), Shroff et al.
patent: 3951986 (1976-04-01), Maruyama et al.
patent: 4115569 (1978-09-01), Weber et al.
Pascal Jean C.
Pinhas Henri
Laroche Navarron S.A.
Sutto Anton H.
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