Piperazine substituted carboxamide derivatives, compositions and

Details Piperazine substituted carboxamide derivatives, compositions and Piperazine substituted carboxamide derivatives, compositions and

1982-05-27

1984-10-30

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424250, 260239BF, 544295, 544360, 544361, 544362, 544372, 544373, 544368, A61K 31505, C07D52100

Patent

active

044799543

ABSTRACT:
The carboximide derivatives of the formula: ##STR1## and pharmaceutically acceptable salts thereof; wherein X represents a group of the formula: ##STR2## Z represents a hydrogen atom or a group of the formula: ##STR3## wherein R represents an alkyl group, an aralkyl group, an aryl group, a cycloalkyl group, an alkenyl group, an arylalkenyl group, a pyridyl group or a substituted amino group; Y represents an alkyl group, an aralkyl group, an aryl group, a substituted or unsubstituted pyridyl group, a substituted or unsubstituted pyrimidyl group or a benzothiazolyl group; and m represents an integer of 2 or 3 and processes for the production thereof. The derivatives and their salts possess hypoglycemic activity and are useful for treating diabetes.

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