Piperazine derivatives that destabilize androgen receptors

Details Piperazine derivatives that destabilize androgen receptors Piperazine derivatives that destabilize androgen receptors

2005-03-01

2005-03-01

Kifle, Bruck (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S214020, C514S253010, C514S253060, C514S254020, C514S254030, C514S254040, C514S254050, C514S254060, C514S254070, C514S254080, C514S254100, C514S217080, C514S217090, C540S603000, C544S063000, C544S295000, C544S357000, C544S360000, C544S363000, C544S367000, C544S370000, C544S371000, C544S372000

Reexamination Certificate

active

06861432

ABSTRACT:
This invention relates to new piperazine derivatives of general formula I,in which V, W, n, R, R′, i, j, Y and Z have the meaning that is indicated in the description.The compounds according to the invention are distinguished by a diazacycloalkane substituent. They have at their disposal a special action with respect to the action that destabilizes the androgen receptor and can be used, for example, for treating prostrate cancer.

REFERENCES:
patent: 5627201 (1997-05-01), Gaillard-Kelly et al.
patent: 5859014 (1999-01-01), Bantle et al.
patent: 0 580 459 (1994-01-01), None
patent: 1 122 242 (2001-08-01), None
patent: WO 9700071 (1997-01-01), None

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