Piperazine derivatives of theophylline and theobromine

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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544266, 544267, C07D47308, A61K 3152

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active

048107069

ABSTRACT:
New compounds of formulas I and II ##STR1## and the pharmaceutically acceptable acid addition salts thereof, wherein M is selected from the group consisting of hydrogen, morpholino, benzylamino, di-n-lower alkylamino, n-lower alkylamino and ##STR2## wherein Ar is optionally substituted phenyl; Z.sub.1 and Z.sub.2 are each independently selected from the group consisting of CH.sub.2, CHOB and C.dbd.O, wherein B is selected from the group consisting of hydrogen and alkanoyl;

REFERENCES:
patent: 4374835 (1983-02-01), Favier et al.
patent: 4400381 (1983-08-01), Favier et al.
patent: 4493837 (1985-01-01), Sugimoto et al.
patent: 4548820 (1985-10-01), Regnier et al.
patent: 4603204 (1986-07-01), Thiele et al.

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