Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-06-23
2010-11-30
Wilson, James O (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S387000
Reexamination Certificate
active
07842696
ABSTRACT:
The present invention relates to piperazine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.
REFERENCES:
patent: 3356658 (1967-12-01), Andersen et al.
patent: 4167567 (1979-09-01), McCall
patent: 6987001 (2006-01-01), Hayden et al.
patent: 7390813 (2008-06-01), Gray-Keller et al.
patent: 2006/0009456 (2006-01-01), Hutchinson et al.
patent: 2006/0009459 (2006-01-01), Chakka et al.
patent: 2006/0199802 (2006-09-01), Abreo et al.
patent: 2006/0205713 (2006-09-01), Gschwend et al.
patent: 2006/0241121 (2006-10-01), Greenlee et al.
patent: 2006/0252767 (2006-11-01), Sviridov et al.
patent: 2008/0167321 (2008-07-01), Kamboj et al.
patent: 2008/0182838 (2008-07-01), Leblanc et al.
patent: 2008/0182851 (2008-07-01), Thomas et al.
patent: 2008/0207587 (2008-08-01), Kamboj et al.
patent: WO 01/62954 (2001-08-01), None
patent: WO 02/34940 (2002-05-01), None
patent: WO 03/075925 (2003-09-01), None
patent: WO 2005/011653 (2005-02-01), None
patent: WO 2005/011654 (2005-02-01), None
patent: WO 2005/011655 (2005-02-01), None
patent: WO 2005/011656 (2005-02-01), None
patent: WO 2005/016657 (2005-02-01), None
patent: WO 2006/034312 (2006-03-01), None
patent: WO 2006 034315 (2006-03-01), None
patent: WO 2006/034338 (2006-03-01), None
patent: WO 2006/034341 (2006-03-01), None
patent: WO 2006/034440 (2006-03-01), None
patent: WO 2006/034441 (2006-03-01), None
patent: WO 2006/034446 (2006-03-01), None
patent: WO 2006/086445 (2006-08-01), None
patent: WO 2006/086447 (2006-08-01), None
patent: WO 2006/014168 (2006-09-01), None
patent: WO 2006/101521 (2006-09-01), None
patent: WO 2006/125178 (2006-11-01), None
patent: WO 2006/125180 (2006-11-01), None
patent: WO 2006/125194 (2006-11-01), None
patent: WO 2006/130986 (2006-12-01), None
patent: WO 2007/009236 (2007-01-01), None
patent: WO 2007/056846 (2007-05-01), None
patent: WO 2007/071023 (2007-06-01), None
patent: WO 2007/134457 (2007-11-01), None
patent: WO 2008/017161 (2008-02-01), None
patent: WO 2008/029266 (2008-03-01), None
patent: WO 2008/046226 (2008-04-01), None
patent: WO 2008/062276 (2008-05-01), None
patent: WO 2008/064474 (2008-06-01), None
patent: WO 2008/089580 (2008-07-01), None
patent: WO 2008/120759 (2008-10-01), None
U.S. Appl. No. 12/644,162, filed Dec. 2009, Bischoff, et al.
International Search Report for PCT/US2008/067951, mailed Sep. 29, 2008.
Written Opinion of the International Searching Authority for PCT/US2008/067951, mailed Sep. 29, 2008.
Flowers, Matthew T., et al., Role of Stearoyl-coenzyme A Desaturase in Regulating Lipid Metabolism, Current Opinion in Lipidology, 19, 248-256, 2008.
Sampath, Harini, et al., Role of Stearoyl-CoA Desaturase in Human Metabolic Disease, Future Lipidol, 3(2), 163-173, 2008.
Dobrzyn, Agnieszka, et al., Inhibition of Stearoyl-CoA Desaturase by Cyclic Amine Derivatives, Expert Opin. Ther. Patents, 18(4):457-460, 2008.
Xin, Zhili, et al., Discovery of Piperidine-aryl Urea-based Stearoyl-CoA Desaturase 1 Inhibitors, Bioorganic & Medicinal Chemistry Letters 18, 4298-4302, 2008.
Liu, Gang, et al., Discovery of Potent, Selective, Orally Biovailable Stearoyl-CoA Desaturase 1 Inhibitors, J. Med. Chem., 50, 3086-3100, 2007.
Kusunoki, Jun, et al., Modulation of Fatty Acid Metabolism as a Potential Approach to the Treatment of Obesity and the Metabolic Syndrome, Endocrine, vol. 29, No. 1, 91-100, 2006.
Bischoff Alexander
Sammeta Srinivasa Raju
Subramanya Hosahalli
Sundaresan Kumar
Vaka Anil Kumar
Ciraolo Michael
Forest Laboratories Holdings Limited
Khanna Hemant
Leeser Erich A
Ryan Charles
LandOfFree
Piperazine derivatives as inhibitors of stearoyl-CoA desaturase does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Piperazine derivatives as inhibitors of stearoyl-CoA desaturase, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Piperazine derivatives as inhibitors of stearoyl-CoA desaturase will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4185423