Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-05-19
1997-03-25
Grumbling, Matthew V.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544295, 544367, 544369, 544370, 544371, 544372, 544373, 544366, 544374, 544376, A61K 31495, C07D40314, C07D40304, C07D40306
Patent
active
056145241
ABSTRACT:
A class of substituted piperazine derivatives of formula I ##STR1## are selective agonists of 5-HT.sub.1 -like receptors and are therefore useful in the treatment of clinical conditions, in particular migraine and associated conditions, for which a selective agonist of these receptors is indicated.
REFERENCES:
patent: 5364866 (1994-11-01), Strupczewski et al.
patent: 5418237 (1995-05-01), B ottcher et al.
patent: 5434154 (1995-07-01), Smith et al.
patent: 5451588 (1995-09-01), Baker et al.
Matassa V. G.
Reeve A. J.
Street L. J.
Grumbling Matthew V.
Merck Sharp & Dohme Ltd.
North Robert J.
Winokur Melvin
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