Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-06-02
1998-03-03
Bernhardt, Emily
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544364, 544373, A61K 31495, C07D40114
Patent
active
057234647
ABSTRACT:
Compounds are disclosed which have the general formula A: ##STR1## where R.sup.a and R.sup.b are each hydrogen or methyl and R.sup.c is hydrogen, halo or C.sub.1-4 alkyl optionally in the form of a pharmaceutically acceptable acid addition salt. The compounds are useful in the treatment of CNS disorders.
REFERENCES:
patent: 4988814 (1991-01-01), Abou-Garbia
A. Fletcher et al., T.I.P.S. 14, 441-448 (1993).
Hoyer et al., Brit. J. Pharmacol. 1992, 105 29P.
Millan et al, Journal of Pharmacology and Experimental Therapeutics, vol. 262, pp. 451-463 (1992).
Brightwell Christopher Ian
Kelly Michael Gerard
American Home Products Corporation
Bernhardt Emily
Boswell, Jr. R. F.
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