Piperazine derivatives

Details Piperazine derivatives Piperazine derivatives

1991-09-30

1992-12-08

Tsang, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142358, 5142362, 5142365, 514252, 514253, 540598, 544121, 544238, 544295, 544360, 544361, 544364, 544366, 544370, 544372, 544379, 544359, A61K 31395, A61K 31495, C07D40306, C07D40314

Patent

active

051698455

ABSTRACT:
Piperazine derivative of formula ##STR1## and the pharmaceutically acceptable acid addition salts, where A is an alkylene chain of 1 or 2 carbon atoms optionally substituted by one or more lower alkyl groups, m is 0, 1 or 2, R is hydrogen or lower alkyl, R.sup.1 is aryl or a mono- or bicyclic heteroaryl radical, R.sup.2 is hydrogen or lower alkyl, R.sup.3 is a heteroaryl radical, R.sup.4 is hydrogen, lower alkyl or aryl, and R.sup.5 is hydrogen, lower alkyl, cycloalkyl, cycloalkyl(lower)alkyl, aryl, or aryl(lower)alkyl or R.sup.4 and R.sup.5 together with the nitrogen atom to which they are both attached represent a saturated heterocyclic ring which may contain a further hetero atom are 5--HT.sub.1A -binding agents and may be used, for example, as anxiolytics.

REFERENCES:
patent: 4882432 (1989-11-01), Abou-Gharbia et al.
patent: 4921958 (1990-05-01), Abou-Gharbia et al.
patent: 4968684 (1990-11-01), Van Daele et al.
patent: 4988814 (1991-01-01), Abou-Gharbia et al.
Morren et al., Chem. Abst., 59:87326 (1963).

Affiliated with

Also associated with

Rating

Piperazine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Piperazine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Piperazine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-961156