Piperazine derivative having substituted phenyl groups

Details Piperazine derivative having substituted phenyl groups Piperazine derivative having substituted phenyl groups

1994-06-07

1995-08-29

Bernhardt, Emily

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

544380, 544389, 536 173, C07D24308, C07D295194

Patent

active

054461464

ABSTRACT:
A therapeutic agent for liver disease containing as an active ingredient a piperazine derivative having the formula: ##STR1## wherein, A represents a phenyl, p-benzoquinonyl or cumarinyl group which may have at least one substituent selected from the group consisting of halogen, alkyl, fluoroalkyl, formyl, alkoxycarbonyl, acyl, hydroxy, alkoxy, acyloxy, glycosyloxy, amino, alkylamino, mercapto, alkylthio and nitro; B represents a single bond or a straight chain alkylene group containing 1-4 carbon atoms which may have at least one substituent selected from the group consisting of alkyl, aryl, aralkyl, hydroxy and oxo; R represents an atom or a group selected from the group consisting of hydrogen, alkali metal, alkaline earth metal, alkyl, cycloalkyl, aralkyl and aryl; and n is 2 or 8, or its pharmaceutically acceptable salt is diclosed.

REFERENCES:
patent: 3646094 (1972-02-01), Brooks et al.
patent: 4112091 (1978-09-01), Nesvadba et al.
patent: 5070089 (1991-12-01), Masaki et al.
Singh et al., Chemical Abstracts, vol. 112, No. 153196 (1989).
Takemoto et al., Chemical Abstracts, vol. 55, No. 27335e (1961).
Florvall et al., Chemical Abstracts, vol. 73, No. 33583 (1970).
Florvall et al., Acta Pharm. Suecica, 7, pp. 7-22 (1970).

Affiliated with

Also associated with

Rating

Piperazine derivative having substituted phenyl groups does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Piperazine derivative having substituted phenyl groups, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Piperazine derivative having substituted phenyl groups will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1820233