Piperazine-based nucleic acid analogs

Details Piperazine-based nucleic acid analogs Piperazine-based nucleic acid analogs

2005-01-11

2005-01-11

Wilson, James O. (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C544S244000, C544S358000, C514S252120, C514S034000, C536S022100, C536S026100, C536S028100, C536S028200

Reexamination Certificate

active

06841675

ABSTRACT:
A novel nucleoside analog is disclosed which comprises a piperazine ring in the place of the ring ribose or deoxyribose sugar. Monomers utilizing a broad variety of nucleobases are disclosed, as well as oligomers comprising the monomers disclosed herein linked by a variety of linkages, including amide, phosphonamide, and sulfonamide linkages. A method of synthesizing the nucleoside analogs is also disclosed.

REFERENCES:
patent: 5861397 (1999-01-01), Wheeler et al.
patent: 06-247942 (1994-09-01), None

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